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About Us

PROVIREX Genome Editing Therapies GmbH is a pioneering biotech company dedicated to developing groundbreaking genome editing therapies for the cure of HIV. Our core technology harnesses highly specific designer recombinases—such as Brec1—to precisely remove integrated HIV DNA from infected cells. Unlike conventional gene editing methods, our recombinase-based approach achieves exceptional accuracy and safety by directly excising viral genomes without relying on cellular DNA repair mechanisms.

At our unique therapy hub in Hamburg, we operate Europe’s only S3** biosafety cleanrooms specifically designed for advanced therapy medicinal product (ATMP) manufacturing. This integrated facility sets new standards for safety and quality, enabling the development and clinical application of innovative, personalized HIV therapies. Our passionate team combines scientific excellence and innovative spirit to transform the future of HIV therapy.

TECHNOLOGY

Technology

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Latest News

PROVIREX and LIV receive €1.7 million to develop gene therapy platform targeting HTLV-1
Joint project TheraImmun funded by IFB Hamburg and EFRE Hamburg, July 29, 2025 – PROVIREX Genome Editing Therapies GmbH and the Leibniz Institute of Virology (LIV) have been awarded €1.7 million in funding through the PROFI Transfer Plus program by the Hamburg Investment and Development…
New Article in Biopharma Dealmakers Highlights Our HIV Cure Strategy
We are excited to announce the publication of a new article in Biopharma Dealmakers, a magazine by Springer Nature, featuring our innovative approach to achieving a functional cure for HIV. The article provides an in-depth assessment of our scientific strategy, the underlying technology platform, and the…
CEO Announcement
We are delighted to announce that Dr. Jan-Uwe Claas is joining PROVIREX from March 1st onwards as our new Chief Executive Officer and as Partner of PROVIREX. With over 25 years of comprehensive experience in the biotech and pharmaceutical industries, Dr. Claas brings a wealth…